Implication of apoptosis in sperm cryoinjury

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Implication of apoptosis in sperm cryoinjury.

Apoptosis is an ongoing physiological phenomenon that has been documented to play a role in male infertility, if deregulated. Caspase activation, externalization of phosphatidylserine, alteration of mitochondrial membrane potential and DNA fragmentation are markers of apoptosis found in ejaculated human spermatozoa. These markers appear in excess in subfertile men and functionally incompetent s...

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tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The authors (Drs. Borini, Tarozzi and Nadalini), in their invited commentary (1) in response to the practice recommendations by Agarwal et al. (2), raised several valid arguments about sperm DNA fragmentation (SDF) testing. In our response to Borini et al., we intend to share additional information on SDF for the read...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2010

ISSN: 1472-6483

DOI: 10.1016/j.rbmo.2010.05.011